Lincolnshire County Council is to repair sections of Rosegarth Street, James Street, St Georges Road and Bond Street in Boston next month.
The £65,000 project is due to begin on the evening of Monday, June 17, and is expected to be completed on the night of Saturday, June 22, subject to favourable weather.
To minimise disruption, the repairs will only be carried out overnight from 8pm to 6am, with the roads unaffected during the daytime.
Road closures will be put in place each evening, with traffic diverted via Queens Street and High Street.
Cllr Richard Davies, executive member for highways, said: “The roads around the bus station are nearing the end of their life and need to be replaced.
“We’ve decided to only work at night to minimise the disruption caused to motorists and those using the buses.
“We apologise for any inconvenience caused, and would advise people to use an alternative route when travelling in the area at night.”
For the latest news on roadworks across the county, visit www.lincolnshire.gov.uk/roadworks